Progesterone, long regarded as a reliable treatment for traumatic brain injury (TBI), and regularly administered to patients with such conditions, may not be as effective in treating the injury as earlier believed.
According to the results of a new study that was published recently in The New England Journal of Medicine, when the drug was administered over a period of five days after patients suffered a traumatic brain injury, there was no significant improvement in the clinical outcomes of the patients.
In the trial, researchers monitored 1,195 patients between 16 and 17 years of age. The patients suffered from TBI, and were divided into two groups randomly. One group received progesterone, while the other was placed on a placebo. The patients received the progesterone within eight hours after suffering the injury. The treatment continued over 120 hours.